There are already abstractions that allows you to deal with IPv6 without actually typing in the addresses. It's the DNS, but every time this topic pops up, someone rejects DNS and proceeds to continue sprouting something about how IPv6 is unusable because you can't memorize the addresses.
I'm not a system administrator for YCombinator, so I couldn't tell you, but I assure you I have the IPv4 IPs of all systems I maintain (personal and enterprise) memorized.
Not even by choice, mind you, but they naturally cement themselves in my mind over time as I work on systems because they're just that basic.
IPv6, on the other hand, I have literally one memorized (::1), likely because it's even shorter than a typical IPv4 address.