The actual study states in the summary that it's the cardiac protective improvement that reverses, not that you're worse off for having taken a GLP-1.
So yeah, when you stop taking something that protects your heart and kidneys, it stops protecting... your heart and kidneys.
There's an increasing body of work that indicates that long-term GLP use (initially higher doses for weight loss, then tapering down) retains the cardiac and kidney benefits and can actually lead to additional weight loss.
> So yeah, when you stop taking something that protects your heart and kidneys, it stops protecting... your heart and kidneys.
This is not at all obvious and still requires further study. Do the drugs themselves have heart- and kidney- protective effects, or are the heart and kidneys protected by maintaining a lower weight, or lower resting blood glucose, or lower inflammation, all of which are effects of the drug?
So yeah, when you stop taking something that protects your heart and kidneys, it stops protecting... your heart and kidneys.
There's an increasing body of work that indicates that long-term GLP use (initially higher doses for weight loss, then tapering down) retains the cardiac and kidney benefits and can actually lead to additional weight loss.