My UsesThis:

    Club Mate
    Aeron
    MacBook Pro with an SSD (you never know how much time you wait for seeks until one day you don't)
    Dell U3011 @ 2560x1600
    Divvy
    F.lux
    Vim
    M-Audio FastTrak Pro
    AIAIAI TMA-1
    Apple corded keyboard
    A mouse with extra buttons mapped to switch desktops in Lion

I like to keep things simple.